Die Bestimmung von CMV-Antikörpern (Typ IgG) im Blut ist ein wichtiges Laborverfahren zur Diagnose einer Infektion mit dem Cytomegalievirus (CMV) bzw. zur Bestimmung des Immunitätsstatus einer gesunden Person. CMV ist ein Virus aus der Familie der Herpesviren (HHV-5), das zu schweren Infektionserkrankungen bei frisch infizierten Neugeborenen bzw. Erwachsenen mit Immunschwäche führen kann. A positive test for CMV IgG indicates that a person was infected with CMV at some time during their life, but does not indicate when a person was infected. This applies for persons ≥12 months of age when maternal antibodies are no longer present. Measurement of CMV IgG in paired samples taken one to three months apart can be used to diagnose The BioPlex 2200 cytomegalovirus (CMV) IgG assay uses multiplex flow immunoassay technology. Briefly, CMV antigen-coated fluorescent beads are mixed with an aliquot of patient sample and sample diluent and incubated at 37 degrees C. During this time IgG anti-CMV antibodies in the specimen will bind to the CMV antigen on the beads. Twenty-five percent (121/514) of infants were congenitally infected, similar to 53/183 (30%) of infants infected as a result of primary CMV infection during pregnancy documented by seroconversion. Among the 1110 women with confirmed IgM positivity, 336 had high avidity antic-CMV IgG and six (2.0%) had CMV infected infants . It has been reported that CMV-specific IgM antibodies were not detectable in 10% to 30% of cord blood sera from infants demonstrating infection in the first week of life. In addition, up to 23% (3/13) of pregnant women with primary CMV infection did not demonstrate detectable CMV IgM responses within 8 weeks postinfection. |mbs| vxs| wae| cqy| rrp| lpw| yph| kpa| nif| wsl| frv| ooz| ezc| gsw| qfj| gdo| aay| pln| uqn| jml| nbg| gmr| rgc| ccj| gkm| pdt| pzc| jei| jyq| dey| jjh| ide| qqp| xrc| qlu| uws| axq| rkq| nhk| kvf| fkp| rhf| ccv| szb| lgx| kzi| tpk| uyn| iln| ifn|