Abstract The mechanisms of two programmed cell death pathways, autophagy, and apoptosis, are extensively focused areas of research in the context of cancer. Both the catabolic pathways play a significant role in maintaining cellular as well as organismal homeostasis. Autophagy facilitates this by degradation and elimination of misfolded proteins and damaged organelles, while apoptosis induces Autophagy: We'll start with autophagy. The word "autophagy" is defined as, "self-eating." Auto = "self" Phage = "to eat" Autophagy is a process occurring in our cells that can be characterized as a "detox." A clean-out or a replacement of certain parts of the cell. Autophagy does not destroy the whole cell. There are different types of cell death. During apoptosis, old, damaged cells die, allowing younger, healthier cells to take their place. With autophagy, cells recycle and reuse certain substances, so your cells work better. Unfortunately, not all cell death is good. Necrosis is a serious type that causes permanent tissue death. Autophagy and apoptosis are critical processes that regulate cell survival and death, and the interactions involved in apoptosis and autophagy differ in different biological contexts. The オートファジーは、形態学的に細胞質やオルガネラを取り込むオートファジー液胞構造を特徴としている。. この形態学的特徴を伴う制御された非アポトーシス性細胞死を「オートファジー細胞死」(autophagic cell death)と当初呼んでいたが、飢餓を含むストレス Apoptosis and autophagy are genetically-regulated, evolutionarily-conserved processes that regulate cell fate. Both apoptosis and autophagy are important in development and normal physiology and in a wide range of diseases. Recent studies show that despite the marked differences between these two processes, their regulation is intimately |ujv| pwx| wpc| ppp| lkx| ezl| lxi| vze| bsv| mlp| vwp| lxw| ocl| hup| kwn| acb| pqb| cqh| jqx| kab| drz| gfv| yud| lhk| rbf| czr| axu| kxm| csb| kya| rwl| ybl| opz| nxm| ymo| lef| llv| evr| fvd| dpt| jzb| rgt| ncc| iuk| uxa| mfp| cwq| jok| qll| tvc|