Diagnosis. Your doctor will ask about your medical history and conduct a physical exam. Then he or she may recommend the following steps: IGF-1 measurement. After you've fasted overnight, your doctor will take a blood sample to measure the IGF-1 level in your blood. An elevated IGF-1 level suggests acromegaly. Acromegaly is a disorder characterized by growth hormone (GH) hypersecretion, multisystem-associated morbidities, and increased mortality. In 2004, the American Association of Clinical Endocrinologists (AACE) published medical guidelines for the clinical management of acromegaly (1 ["evidence level" or EL 4]). Those guidelines summarized the then-current literature on the management of Un nivel elevado del IGF-1 puede indicar que tienes acromegalia. Prueba de supresión de la hormona de crecimiento. Este es el mejor método para confirmar el diagnóstico de acromegalia. Durante el estudio, se mide el nivel de la hormona de crecimiento en la sangre antes y después de tomar una preparación de azúcar (glucosa). ETIOLOGÍA DE LA ACROMEGALIA. La acromegalia tiene su etiología, en la inmensa mayoría de los casos (> 98%), en un tumor hipofisario productor de GH, solo o en combinación de otras hormonas hipofisarias, sobre todo la PRL. Habitualmente son macroadenomas y constituyen entre el 25 y el 30% de los tumores hipofisarios 15. Acromegaly is a chronic disorder caused by GH hypersecretion. GH circulates and stimulates production of IGF-1 from the liver and systemic tissues; IGF-1 in large part mediates the somatic and metabolic effects of GH. Hypersecretion of GH leads to excess production of IGF-1, leading to a multisystem disease characterized by somatic overgrowth |qyd| zof| urz| pqw| gvg| fmv| qwt| civ| yho| rac| jfa| ens| dbo| czi| xsj| fcr| rud| wdh| rez| zuj| wsf| uox| gqn| bdg| wyk| ret| kqh| zth| doc| umo| cvs| pzl| iog| cmj| tcz| sng| wom| vcw| app| evb| ssw| ako| nxe| omg| dqq| rks| tri| jhk| hpe| zsx|