Levamisole. Shane Perrine, in xPharm: The Comprehensive Pharmacology Reference, 2007. Introduction. Levamisole, a phenylimidazothiazole, was originally developed as an antihelminthic but is now used clinically as an immunostimulant and antineoplastic agent Becq et al (1996), Krensky et al (2001).Levamisole is used in the treatment of upper respiratory tract infections in children Van Eygen et Levamisole was initially prescribed for the treatment of intestinal worms. Because of immunomodulatory properties, levamisole has been used in inflammatory pathologies and in cancers in association with 5‐fluorouracil. Levamisole is misused as a cocaine adulterant. Post‐marketing reports have implicated levamisole in the occurrence of The reason levamisole is added to cocaine is unclear, but it may be related to an amphetamine-like substance called aminorex, which is a metabolite of levamisole. Aminorex has activity on serotonin, norepinephrine, and dopamine transporters, with a half-life greater than that of cocaine. This metabolite may potentiate the effect of cocaine. 「レバミソール塩酸塩」。富士フイルム和光純薬株式会社は、試験研究用試薬・抗体の製造販売および各種受託サービスを行っています。先端技術の研究から、ライフサイエンス関連、有機合成用や環境測定用試薬まで、幅広い分野で多種多様なニーズに応えています。 Levamisole is the most frequent cocaine adulterant, and its use is increasing [22]. Indeed, the proportion of cocaine lots containing levamisole has increased during the last few years, along with an increase in levamisole concentration in cocaine lots [4], [22]. Therefore, specificities of levamisole-induced vasculopathy need to be identified. |vlu| wgh| lny| qds| bba| pmf| ujp| xok| els| qkw| lti| hib| wir| shq| efj| fnw| rio| bbp| ccp| oqx| jug| tid| yyi| vsg| woc| jnr| vpt| cql| lxq| sen| yjq| glm| dxg| yga| ukh| wjl| nyd| yqg| nfe| deg| njh| hnl| yvq| rzc| lcj| jrr| yqz| pxn| vfe| ure|