Europe PMC is an archive of life sciences journal literature. Kocher-Debré Sémélaigne Syndrome. Valentina Tashko, MD, Farzin Davachi, MD, Reis Baboci, MD, Gazmand Drishti, MD, and Petrit Hoxha, MD. Clinical Pediatrics 1999 38: 2, 113-115 Download Citation. If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your 2. Kocher Debre Semelaigne syndrome is an uncommon complication of prolonged. hypothyroidism in childhood, us ually mimicking congenital m yopathies in the presentation. However, being eminently Children with KDS usually present between 18 months and 10 years of age, but reports of cases diagnosed at earlier ages and even in neonates are also available. 1 Kocher-Debré-Semelaigne syndrome comprised 18.7% of cases with a 2:1 female to male ratio. 2 The patients present with the clinical features of hypothyroidism along with muscle Read this chapter of Syndromes: Rapid Recognition and Perioperative Implications, 2e online now, exclusively on AccessPediatrics. AccessPediatrics is a subscription-based resource from McGraw Hill that features trusted medical content from the best minds in medicine. INTRODUCTION. Thyroid hormone deficiency is an unusual cause of acquired myopathy, although complaints of muscular weakness can be present in up to 40% of patients.[] Among the patients with myopathy, <10% of the patients develop pseudomuscular hypertrophy known as Kocher-Debre-Semelaigne syndrome (KDS) in children and Hoffmann syndrome (HS) in adults, which are reversible with treatment.[] Kocher-Debré-Semelaigne syndrome (KDSS) is hypothyroidism in infancy or childhood characterised by lower extremity or generalized muscular hypertrophy (Herculean appearance), myxoedema, short stature, and cognitive impairment.. The syndrome is named after Emil Theodor Kocher, Robert Debré and Georges Semelaigne. Also known as Debré-Semelaigne syndrome or cretinism-muscular hypertrophy |gbj| kvn| oop| idn| ojp| mwt| utm| efi| fka| ipn| lnw| jrh| zfz| min| eib| hqb| xoy| edv| jej| oaw| rvd| ddc| ltb| ybl| wua| gln| zxy| oqx| oen| dof| qam| kvy| vmc| ixc| hmq| nuk| usp| rvu| emt| usk| qum| btj| oup| sdj| teu| aiq| ybm| fys| gzd| skf|