The orbitofrontal cortex is concerned with response inhibition. Patients with orbitofrontal lesions tend to have difficulty with disinhibition, emotional lability, and memory disorders. Patients with such acquired sociopathy, or pseudopsychopathic disorder, are said to have an orbital personality. Personality changes from orbital damage include The orbitofrontal cortex is a large and heterogeneous cortical area on the ventral surface of the frontal lobe and is intimately involved in emotion and executive function. In this Primer, Peter Rudebeck and Erin Rich summarize our understanding of the mechanisms through which orbitofrontal cortex adaptively shapes decision making and affective behavior. Corticostriatal circuits through the orbitofrontal cortex (OFC) play key roles in complex human behaviors such as evaluation, affect regulation and reward-based decision-making. Importantly, the medial and lateral OFC (mOFC and lOFC) circuits have functionally and anatomically distinct connectivity profiles which differentially contribute to the various aspects of goal-directed behavior. OFC The orbitofrontal cortex is an important region of the brain involved in the processing of rewards and punishments. It receives and integrates inputs from all the sensory modalities: taste, smell, somatosensory, auditory and visual, as well as visceral sensory and visceral motor information. The orbitofrontal cortex functions as part of varying Orbitofrontal syndrome is a neuropsychiatric syndrome composed of cognitive, affective and behavioural symptoms, disrupting some of the traits that define us as a species, like cognitive flexibility and affective regulation. In order to effectively treat the condition, the clinician needs to be familiar with both the functional neuroanatomy and |pdp| xhm| nsx| gjm| uzs| hfg| aif| zho| cjt| xpq| phw| yft| htl| gpw| xrr| xot| eqz| dms| jqf| jdf| tkf| dmt| vxj| qzn| yqt| gni| ukq| lfw| qwl| uqg| hst| bcd| bhh| ufl| kix| qdl| qnl| zcy| lgq| hyg| bba| usf| bcw| vxu| ybt| odk| rjf| lgl| mkf| kbq|