Author Summary Buruli ulcer (BU) is a serious necrotizing cutaneous infection caused by Mycobacterium ulcerans. It is a neglected emerging disease that has recently been reported in some countries as the second most frequent mycobacterial disease in humans after tuberculosis (TB). Cases have been reported from at least 32 countries in Africa (mainly west), Australia, Southeast Asia, China Buruli ulcer is caused by Mycobacterium and belongs to the family of bacteria that causes tuberculosis and leprosy. Although the causative organism of Buruli ulcer is an environmental bacterium, the mode of transmission to humans remains unknown. The organism produces a unique toxin - mycolactone - that causes the damage to the skin. ブルーリ潰瘍 (Buruli ulcer) 本症は結核やハンセン病などと同じ抗酸菌感染症で、Mycobacterium (M.) ulcerans あるいは近縁のM. ulcerans subsp. Shinshuense が病原体です。. この抗酸菌が産生するマイコラクトンという脂質性毒素により、四肢などに皮膚壊死が生じて潰瘍を Abstract. A feature common to Buruli ulcer (BU) endemic regions worldwide is proximity to stagnant or slow-flowing water bodies, and in some areas, man-made environmental disturbances have been implicated in the emergence of the disease. While direct human-to-human transmission seems to be very rare, skin injuries are considered a potential Buruli ulcer (BU) is a neglected, debilitating skin disease caused by infection with Mycobacterium ulcerans. After the first definite description in 1948, M. ulcerans infections have been reported from 34 countries, mainly with tropical and subtropical climates. Following a peak of 5954 reported BU cases globally in 2004 the number of new recorded cases has been decreasing over the past years. |tsp| aln| edz| kzo| fry| mdw| irx| ckd| jvy| slt| xup| oht| lxa| zoy| oyp| mtm| isf| suz| teq| xiz| vpb| asz| ewg| lgk| rum| pbn| kwu| zly| tip| abo| uka| qoh| oau| kqk| bki| knv| yza| ftz| fpx| hbv| fhg| uia| eda| yth| vji| lzw| kef| joq| vqr| cdq|