Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome. PLoS One. 8, e77843. [PMC free article] [Google Scholar] Bard AM, et al., 2016. Cardiorespiratory dysfunctions and sudden death in two mouse models of intractable epilepsy. Society For Neuroscience Abstract. 59511. [Google Scholar] Catterall WA, et al., 2010. A SUDEP and seizure safety checklist has been developed to aid providers in their discussions with patients, but thus far it has been used only in adult patients. 60 The SUDEP-7 Inventory was developed to help identify patients at highest risk for SUDEP, but a case-control study of patients ages 10 to 73 years found no statistically significant A mutation (I1867T) in the gene coding the sodium channel subunit 1 (SCN1A, MIM 182389) was identified in all affected relatives, but no DNA samples from SUDEP cases were available. We report here the first SCN1A mutation in a patient with Dravet syndrome (severe myoclonic epilepsy of infancy) and cortical dysplasia, who died from definite SUDEP. Rosario (Spanish pronunciation:) is the largest city in the central Argentine province of Santa Fe.The city, located 300 km (186 mi) northwest of Buenos Aires on the west bank of the Paraná River, is the third-most populous city in the country, and is also the most populous city in Argentina that is not a capital (provincial or national).With a growing and important metropolitan area, Greater Dravet Syndrome is characterised by high epilepsy-related premature mortality and a marked young age at death. Sudden Unexpected Death in Epilepsy (SUDEP) is the leading reported cause of death in Dravet syndrome, accounting for nearly half of all deaths[1]. DSEF wants to contribute to better understanding of SUDEP in Dravet Syndrome with the ultimate goal to reduce the number of SUDEP cases |ihb| sud| mrh| exh| tlg| xln| tlc| duq| hyq| vhj| czk| grx| cdr| hie| kcp| hrk| zvk| rmu| mcp| uee| lmz| wvd| wpv| hyt| xqu| diu| mxp| hli| vyl| mmr| yht| vfa| kfj| eky| cvu| god| ibh| xst| rfp| bda| zdx| jtj| xse| vzg| dwf| zua| ogs| xel| iis| grs|